Cargando…

HaSAPPy: A tool for candidate identification in pooled forward genetic screens of haploid mammalian cells

Haploid cells are increasingly used for screening of complex pathways in animal genomes. Hemizygous mutations introduced through viral insertional mutagenesis can be directly selected for phenotypic changes. Here we present HaSAPPy a tool for analysing sequencing datasets of screens using insertiona...

Descripción completa

Detalles Bibliográficos
Autores principales: Di Minin, Giulio, Postlmayr, Andreas, Wutz, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798846/
https://www.ncbi.nlm.nih.gov/pubmed/29337991
http://dx.doi.org/10.1371/journal.pcbi.1005950