Cargando…
HaSAPPy: A tool for candidate identification in pooled forward genetic screens of haploid mammalian cells
Haploid cells are increasingly used for screening of complex pathways in animal genomes. Hemizygous mutations introduced through viral insertional mutagenesis can be directly selected for phenotypic changes. Here we present HaSAPPy a tool for analysing sequencing datasets of screens using insertiona...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798846/ https://www.ncbi.nlm.nih.gov/pubmed/29337991 http://dx.doi.org/10.1371/journal.pcbi.1005950 |