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Conditional mutagenesis in vivo reveals cell type- and infection stage-specific requirements for LANA in chronic MHV68 infection

Gammaherpesvirus (GHV) pathogenesis is a complex process that involves productive viral replication, dissemination to tissues that harbor lifelong latent infection, and reactivation from latency back into a productive replication cycle. Traditional loss-of-function mutagenesis approaches in mice usi...

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Detalles Bibliográficos
Autores principales:	Salinas, Eduardo, Gupta, Arundhati, Sifford, Jeffrey M., Oldenburg, Darby G., White, Douglas W., Forrest, J. Craig
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798852/ https://www.ncbi.nlm.nih.gov/pubmed/29364981 http://dx.doi.org/10.1371/journal.ppat.1006865

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