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Computational modelling of pathogenic protein spread in neurodegenerative diseases
Pathogenic protein accumulation and spread are fundamental principles of neurodegenerative diseases and ultimately account for the atrophy patterns that distinguish these diseases clinically. However, the biological mechanisms that link pathogenic proteins to specific neural network damage patterns...
Autores principales: | Georgiadis, Konstantinos, Wray, Selina, Ourselin, Sébastien, Warren, Jason D., Modat, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798854/ https://www.ncbi.nlm.nih.gov/pubmed/29401516 http://dx.doi.org/10.1371/journal.pone.0192518 |
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