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Diffuse Alveolar Hemorrhage in IgA Vasculitis with an Atypical Presentation
IgA vasculitis (IgAV) commonly occurs in young children, who present with a tetrad of purpura, abdominal pain, arthralgia and nephritis. Diffuse alveolar hemorrhage (DAH) is a rare complication of IgAV. We herein report an adult case of IgAV with a presentation of DAH and nephritis (pulmonary renal...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Internal Medicine
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799062/ https://www.ncbi.nlm.nih.gov/pubmed/29033424 http://dx.doi.org/10.2169/internalmedicine.8984-17 |
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author | Ito, Yuhei Arita, Machiko Kumagai, Shogo Takei, Reoto Noyama, Maki Tokioka, Fumiaki Nagamoto, Takumi Kawakita, Chieko Asano, Kenichiro Okita, Chika Ishida, Tadashi |
author_facet | Ito, Yuhei Arita, Machiko Kumagai, Shogo Takei, Reoto Noyama, Maki Tokioka, Fumiaki Nagamoto, Takumi Kawakita, Chieko Asano, Kenichiro Okita, Chika Ishida, Tadashi |
author_sort | Ito, Yuhei |
collection | PubMed |
description | IgA vasculitis (IgAV) commonly occurs in young children, who present with a tetrad of purpura, abdominal pain, arthralgia and nephritis. Diffuse alveolar hemorrhage (DAH) is a rare complication of IgAV. We herein report an adult case of IgAV with a presentation of DAH and nephritis (pulmonary renal syndrome, PRS), but without other typical manifestations, such as purpura, abdominal pain and arthralgia. A 33-year-old man presented with hemoptysis and a low-grade fever and was diagnosed to have IgAV based on the results of a renal biopsy. Treatment with corticosteroids, cyclophosphamide, and plasmapheresis was effective. IgAV should therefore be considered in the differential diagnosis of adult PRS. |
format | Online Article Text |
id | pubmed-5799062 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | The Japanese Society of Internal Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-57990622018-02-08 Diffuse Alveolar Hemorrhage in IgA Vasculitis with an Atypical Presentation Ito, Yuhei Arita, Machiko Kumagai, Shogo Takei, Reoto Noyama, Maki Tokioka, Fumiaki Nagamoto, Takumi Kawakita, Chieko Asano, Kenichiro Okita, Chika Ishida, Tadashi Intern Med Case Report IgA vasculitis (IgAV) commonly occurs in young children, who present with a tetrad of purpura, abdominal pain, arthralgia and nephritis. Diffuse alveolar hemorrhage (DAH) is a rare complication of IgAV. We herein report an adult case of IgAV with a presentation of DAH and nephritis (pulmonary renal syndrome, PRS), but without other typical manifestations, such as purpura, abdominal pain and arthralgia. A 33-year-old man presented with hemoptysis and a low-grade fever and was diagnosed to have IgAV based on the results of a renal biopsy. Treatment with corticosteroids, cyclophosphamide, and plasmapheresis was effective. IgAV should therefore be considered in the differential diagnosis of adult PRS. The Japanese Society of Internal Medicine 2017-10-16 2018-01-01 /pmc/articles/PMC5799062/ /pubmed/29033424 http://dx.doi.org/10.2169/internalmedicine.8984-17 Text en Copyright © 2018 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case Report Ito, Yuhei Arita, Machiko Kumagai, Shogo Takei, Reoto Noyama, Maki Tokioka, Fumiaki Nagamoto, Takumi Kawakita, Chieko Asano, Kenichiro Okita, Chika Ishida, Tadashi Diffuse Alveolar Hemorrhage in IgA Vasculitis with an Atypical Presentation |
title | Diffuse Alveolar Hemorrhage in IgA Vasculitis with an Atypical Presentation |
title_full | Diffuse Alveolar Hemorrhage in IgA Vasculitis with an Atypical Presentation |
title_fullStr | Diffuse Alveolar Hemorrhage in IgA Vasculitis with an Atypical Presentation |
title_full_unstemmed | Diffuse Alveolar Hemorrhage in IgA Vasculitis with an Atypical Presentation |
title_short | Diffuse Alveolar Hemorrhage in IgA Vasculitis with an Atypical Presentation |
title_sort | diffuse alveolar hemorrhage in iga vasculitis with an atypical presentation |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799062/ https://www.ncbi.nlm.nih.gov/pubmed/29033424 http://dx.doi.org/10.2169/internalmedicine.8984-17 |
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