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Visualization and quantification of dynamic STAT3 homodimerization in living cells using homoFluoppi

Dimerization in signal transduction is a dynamically regulated process and a key regulatory mechanism. Signal transducer and activator of transcription 3 (STAT3) dimerizes after tyrosine phosphorylation upon cytokine stimulation. Because only the STAT3 dimer possesses the trans-activation activity,...

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Detalles Bibliográficos
Autores principales: Okada, Yusuke, Watanabe, Taku, Shoji, Toru, Taguchi, Kyoko, Ogo, Naohisa, Asai, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799161/
https://www.ncbi.nlm.nih.gov/pubmed/29402895
http://dx.doi.org/10.1038/s41598-018-20234-2