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p38 activation induces production of miR-146a and miR-31 to repress E-selectin expression and inhibit transendothelial migration of colon cancer cells

Extravasation of circulating cancer cells determines their metastatic potential. This process is initiated by the adhesion of cancer cells to vascular endothelial cells through specific interactions between endothelial adhesion receptors such as E-selectin and their ligands on cancer cells. In the p...

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Detalles Bibliográficos
Autores principales: Zhong, Liang, Huot, Jacques, Simard, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799178/
https://www.ncbi.nlm.nih.gov/pubmed/29402939
http://dx.doi.org/10.1038/s41598-018-20837-9