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Eis, a novel family of arylalkylamine N-acetyltransferase (EC 2.3.1.87)

Enhanced intracellular survival (Eis) proteins were found to enhance the intracellular survival of mycobacteria in macrophages by acetylating aminoglycoside antibiotics to confer resistance to these antibiotics and by acetylating DUSP16/MPK-7 to suppress host innate immune defenses. Eis homologs com...

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Detalles Bibliográficos
Autores principales: Pan, Qian, Zhao, Feng-Lan, Ye, Bang-Ce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799202/
https://www.ncbi.nlm.nih.gov/pubmed/29402941
http://dx.doi.org/10.1038/s41598-018-20802-6

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