HDAC6 Inhibition Promotes Transcription Factor EB Activation and Is Protective in Experimental Kidney Disease

To contend with the deleterious effects of accumulating misfolded protein aggregates or damaged organelles cells rely on a system of quality control processes, among them the autophagy-lysosome pathway. This pathway is itself controlled by a master regulator transcription factor termed transcription...

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Detalles Bibliográficos
Autores principales: Brijmohan, Angela S., Batchu, Sri N., Majumder, Syamantak, Alghamdi, Tamadher A., Thieme, Karina, McGaugh, Sarah, Liu, Youan, Advani, Suzanne L., Bowskill, Bridgit B., Kabir, M. Golam, Geldenhuys, Laurette, Siddiqi, Ferhan S., Advani, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799228/
https://www.ncbi.nlm.nih.gov/pubmed/29449811
http://dx.doi.org/10.3389/fphar.2018.00034

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