Generation of a rod-specific NRL reporter line in human pluripotent stem cells

Reporter lines generated in human pluripotent stem cells can be highly useful for the analysis of specific cell types and lineages in live cultures. We created the first human rod reporter line using CRISPR/Cas9 genome editing to replace one allele of the Neural Retina Leucine zipper (NRL) gene with...

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Detalles Bibliográficos
Autores principales: Phillips, M. Joseph, Capowski, Elizabeth E., Petersen, Andrew, Jansen, Alex D., Barlow, Katherine, Edwards, Kimberly L., Gamm, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799252/
https://www.ncbi.nlm.nih.gov/pubmed/29402929
http://dx.doi.org/10.1038/s41598-018-20813-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799252/
https://www.ncbi.nlm.nih.gov/pubmed/29402929
http://dx.doi.org/10.1038/s41598-018-20813-3

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