Cargando…

The selective reversible FAAH inhibitor, SSR411298, restores the development of maladaptive behaviors to acute and chronic stress in rodents

Enhancing endogenous cannabinoid (eCB) signaling has been considered as a potential strategy for the treatment of stress-related conditions. Fatty acid amide hydrolase (FAAH) represents the primary degradation enzyme of the eCB anandamide (AEA), oleoylethanolamide (OEA) and palmitoylethanolamide (PE...

Descripción completa

Detalles Bibliográficos
Autores principales: Griebel, Guy, Stemmelin, Jeanne, Lopez-Grancha, Mati, Fauchey, Valérie, Slowinski, Franck, Pichat, Philippe, Dargazanli, Gihad, Abouabdellah, Ahmed, Cohen, Caroline, Bergis, Olivier E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799259/
https://www.ncbi.nlm.nih.gov/pubmed/29403000
http://dx.doi.org/10.1038/s41598-018-20895-z