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The selective reversible FAAH inhibitor, SSR411298, restores the development of maladaptive behaviors to acute and chronic stress in rodents
Enhancing endogenous cannabinoid (eCB) signaling has been considered as a potential strategy for the treatment of stress-related conditions. Fatty acid amide hydrolase (FAAH) represents the primary degradation enzyme of the eCB anandamide (AEA), oleoylethanolamide (OEA) and palmitoylethanolamide (PE...
Autores principales: | Griebel, Guy, Stemmelin, Jeanne, Lopez-Grancha, Mati, Fauchey, Valérie, Slowinski, Franck, Pichat, Philippe, Dargazanli, Gihad, Abouabdellah, Ahmed, Cohen, Caroline, Bergis, Olivier E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799259/ https://www.ncbi.nlm.nih.gov/pubmed/29403000 http://dx.doi.org/10.1038/s41598-018-20895-z |
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