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Transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions
Transcriptional regulation is tightly coupled with chromosomal positioning and three-dimensional chromatin architecture. However, it is unclear what proportion of transcriptional activity is reflecting such organisation, how much can be informed by RNA expression alone and how this impacts disease....
Autores principales: | Rennie, Sarah, Dalby, Maria, van Duin, Lucas, Andersson, Robin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799294/ https://www.ncbi.nlm.nih.gov/pubmed/29402885 http://dx.doi.org/10.1038/s41467-017-02798-1 |
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