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Transcriptional decomposition reveals active chromatin architectures and cell specific regulatory interactions

Transcriptional regulation is tightly coupled with chromosomal positioning and three-dimensional chromatin architecture. However, it is unclear what proportion of transcriptional activity is reflecting such organisation, how much can be informed by RNA expression alone and how this impacts disease....

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Detalles Bibliográficos
Autores principales: Rennie, Sarah, Dalby, Maria, van Duin, Lucas, Andersson, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799294/
https://www.ncbi.nlm.nih.gov/pubmed/29402885
http://dx.doi.org/10.1038/s41467-017-02798-1

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