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In vitro RNA-seq-based toxicogenomics assessment shows reduced biological effect of tobacco heating products when compared to cigarette smoke

The battery of regulatory tests used to evaluate the risk of novel tobacco products such as heated tobacco products (THPs) presents some limitations including a bias towards the apical endpoint tested, and limited information on the mode of action. This is driving a paradigm shift to more holistic s...

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Detalles Bibliográficos
Autores principales: Haswell, Linsey E., Corke, Sarah, Verrastro, Ivan, Baxter, Andrew, Banerjee, Anisha, Adamson, Jason, Jaunky, Tomasz, Proctor, Christopher, Gaça, Marianna, Minet, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799303/
https://www.ncbi.nlm.nih.gov/pubmed/29402904
http://dx.doi.org/10.1038/s41598-018-19627-0