Amnionless-mediated glycosylation is crucial for cell surface targeting of cubilin in renal and intestinal cells

Mutations in either cubilin (CUBN) or amnionless (AMN) genes cause Imerslund–Gräsbeck syndrome (IGS), a hereditary disease characterised by anaemia attributed to selective intestinal malabsorption of cobalamin and low-molecular weight proteinuria. Although cubilin protein does not have a transmembra...

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Detalles Bibliográficos
Autores principales: Udagawa, Tomohiro, Harita, Yutaka, Miura, Kenichiro, Mitsui, Jun, Ode, Koji L., Morishita, Shinichi, Urae, Seiya, Kanda, Shoichiro, Kajiho, Yuko, Tsurumi, Haruko, Ueda, Hiroki R., Tsuji, Shoji, Saito, Akihiko, Oka, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799345/
https://www.ncbi.nlm.nih.gov/pubmed/29402915
http://dx.doi.org/10.1038/s41598-018-20731-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799345/
https://www.ncbi.nlm.nih.gov/pubmed/29402915
http://dx.doi.org/10.1038/s41598-018-20731-4

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