Mobilan: a recombinant adenovirus carrying Toll-like receptor 5 self-activating cassette for cancer immunotherapy

Toll-like receptor 5 (TLR5) is considered an attractive target for anticancer immunotherapy. TLR5 agonists, bacterial flagellin and engineered flagellin derivatives, have been shown to have potent antitumor and metastasis-suppressive effects in multiple animal models and to be safe in both animals a...

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Detalles Bibliográficos
Autores principales: Mett, V, Komarova, E A, Greene, K, Bespalov, I, Brackett, C, Gillard, B, Gleiberman, A S, Toshkov, I A, Aygün-Sunar, S, Johnson, C, Karasik, E, Bapardekar-Nair, M, Kurnasov, O V, Osterman, A L, Stanhope-Baker, P S, Morrison, C, Moser, M T, Foster, B A, Gudkov, A V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799711/
https://www.ncbi.nlm.nih.gov/pubmed/28967901
http://dx.doi.org/10.1038/onc.2017.346

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