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Nerve growth factor upregulates sirtuin 1 expression in cholestasis: a potential therapeutic target

This study investigated the regulatory role of nerve growth factor (NGF) in sirtuin 1 (SIRT1) expression in cholestatic livers. We evaluated the expression of NGF and its cognate receptors in human livers with hepatolithiasis and the effects of NGF therapy on liver injury and hepatic SIRT1 expressio...

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Detalles Bibliográficos
Autores principales: Tsai, Ming-Shian, Lee, Po-Huang, Sun, Cheuk-Kwan, Chiu, Ting-Chia, Lin, Yu-Chun, Chang, I-Wei, Chen, Po-Han, Kao, Ying-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799797/
https://www.ncbi.nlm.nih.gov/pubmed/29328070
http://dx.doi.org/10.1038/emm.2017.235