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Proangiogenic functions of an RGD-SLAY-containing osteopontin icosamer peptide in HUVECs and in the postischemic brain

Osteopontin (OPN) is a phosphorylated glycoprotein secreted into body fluids by various cell types. OPN contains arginine-glycine-aspartate (RGD) and serine-leucine-alanine-tyrosine (SLAY) motifs that bind to several integrins and mediate a wide range of cellular processes. In the present study, the...

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Detalles Bibliográficos
Autores principales: Lee, Hahnbie, Jin, Yin-Chuan, Kim, Seung-Woo, Kim, Il-Doo, Lee, Hye-Kyung, Lee, Ja-Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799800/
https://www.ncbi.nlm.nih.gov/pubmed/29350679
http://dx.doi.org/10.1038/emm.2017.241