H5N1 influenza virus-specific miRNA-like small RNA increases cytokine production and mouse mortality via targeting poly(rC)-binding protein 2

Infection of H5N1 influenza virus causes the highest mortality among all influenza viruses. The mechanisms underlying such high viral pathogenicity are incompletely understood. Here, we report that the H5N1 influenza virus encodes a microRNA-like small RNA, miR-HA-3p, which is processed from a stem...

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Detalles Bibliográficos
Autores principales: Li, Xihan, Fu, Zheng, Liang, Hongwei, Wang, Yanbo, Qi, Xian, Ding, Meng, Sun, Xinlei, Zhou, Zhen, Huang, Ying, Gu, Hongwei, Li, Limin, Chen, Xi, Li, Donghai, Zhao, Quan, Liu, Fenyong, Wang, Hua, Wang, Jin, Zen, Ke, Zhang, Chen-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799819/
https://www.ncbi.nlm.nih.gov/pubmed/29327729
http://dx.doi.org/10.1038/cr.2018.3

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