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Changes in the Cardiac GHSR1a-Ghrelin System Correlate With Myocardial Dysfunction in Diabetic Cardiomyopathy in Mice

Ghrelin and its receptor, the growth hormone secretagogue receptor 1a (GHSR1a), are present in cardiac tissue. Activation of GHSR1a by ghrelin promotes cardiomyocyte contractility and survival, and changes in myocardial GHSR1a and circulating ghrelin track with end-stage heart failure, leading to th...

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Detalles Bibliográficos
Autores principales:	Sullivan, Rebecca, McGirr, Rebecca, Hu, Shirley, Tan, Alice, Wu, Derek, Charron, Carlie, Lalonde, Tyler, Arany, Edith, Chakrabarti, Subrata, Luyt, Leonard, Dhanvantari, Savita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799831/ https://www.ncbi.nlm.nih.gov/pubmed/29450407 http://dx.doi.org/10.1210/js.2017-00433

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