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Sphingosine kinase 2 supports the development of BCR/ABL-independent acute lymphoblastic leukemia in mice

BACKGROUND: Sphingosine kinase (SphK) 2 has been implicated in the development of a range of cancers and inhibitors of this enzyme are currently in clinical trial. We have previously demonstrated a role for SphK2 in the development of acute lymphoblastic leukemia (ALL). METHODS: In this and our prev...

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Detalles Bibliográficos
Autores principales:	Xie, Vicki, Tong, Daochen, Wallington-Beddoe, Craig T., Bradstock, Ken F., Bendall, Linda J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800079/ https://www.ncbi.nlm.nih.gov/pubmed/29441205 http://dx.doi.org/10.1186/s40364-018-0120-4

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