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Ezh2 does not mediate retinal ganglion cell homeostasis or their susceptibility to injury
Epigenetic predisposition is thought to critically contribute to adult-onset disorders, such as retinal neurodegeneration. The histone methyltransferase, enhancer of zeste homolog 2 (Ezh2), is transiently expressed in the perinatal retina, particularly enriched in retinal ganglion cells (RGCs). We p...
Autores principales: | Cheng, Lin, Wong, Lucy J., Yan, Naihong, Han, Richard C., Yu, Honghua, Guo, Chenying, Batsuuri, Khulan, Zinzuwadia, Aniket, Guan, Ryan, Cho, Kin-Sang, Chen, Dong Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800601/ https://www.ncbi.nlm.nih.gov/pubmed/29408885 http://dx.doi.org/10.1371/journal.pone.0191853 |
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