Lipid droplet formation in Mycobacterium tuberculosis infected macrophages requires IFN-γ/HIF-1α signaling and supports host defense

Lipid droplet (LD) formation occurs during infection of macrophages with numerous intracellular pathogens, including Mycobacterium tuberculosis. It is believed that M. tuberculosis and other bacteria specifically provoke LD formation as a pathogenic strategy in order to create a depot of host lipids...

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Detalles Bibliográficos
Autores principales: Knight, Matthew, Braverman, Jonathan, Asfaha, Kaleb, Gronert, Karsten, Stanley, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800697/
https://www.ncbi.nlm.nih.gov/pubmed/29370315
http://dx.doi.org/10.1371/journal.ppat.1006874

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