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Humanin is an endogenous activator of chaperone-mediated autophagy

Chaperone-mediated autophagy (CMA) serves as quality control during stress conditions through selective degradation of cytosolic proteins in lysosomes. Humanin (HN) is a mitochondria-associated peptide that offers cytoprotective, cardioprotective, and neuroprotective effects in vivo and in vitro. In...

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Detalles Bibliográficos
Autores principales: Gong, Zhenwei, Tasset, Inmaculada, Diaz, Antonio, Anguiano, Jaime, Tas, Emir, Cui, Lingguang, Kuliawat, Regina, Liu, Honghai, Kühn, Bernhard, Cuervo, Ana Maria, Muzumdar, Radhika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800795/
https://www.ncbi.nlm.nih.gov/pubmed/29187525
http://dx.doi.org/10.1083/jcb.201606095