Cargando…

A new mitofusin topology places the redox-regulated C terminus in the mitochondrial intermembrane space

Mitochondrial fusion occurs in many eukaryotes, including animals, plants, and fungi. It is essential for cellular homeostasis, and yet the underlying mechanisms remain elusive. Comparative analyses and phylogenetic reconstructions revealed that fungal Fzo1 and animal Mitofusin proteins are highly d...

Descripción completa

Detalles Bibliográficos
Autores principales: Mattie, Sevan, Riemer, Jan, Wideman, Jeremy G., McBride, Heidi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800796/
https://www.ncbi.nlm.nih.gov/pubmed/29212658
http://dx.doi.org/10.1083/jcb.201611194