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A new mitofusin topology places the redox-regulated C terminus in the mitochondrial intermembrane space
Mitochondrial fusion occurs in many eukaryotes, including animals, plants, and fungi. It is essential for cellular homeostasis, and yet the underlying mechanisms remain elusive. Comparative analyses and phylogenetic reconstructions revealed that fungal Fzo1 and animal Mitofusin proteins are highly d...
Autores principales: | Mattie, Sevan, Riemer, Jan, Wideman, Jeremy G., McBride, Heidi M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800796/ https://www.ncbi.nlm.nih.gov/pubmed/29212658 http://dx.doi.org/10.1083/jcb.201611194 |
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