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Keratin 6a reorganization for ubiquitin–proteasomal processing is a direct antimicrobial response

Skin and mucosal epithelia deploy antimicrobial peptides (AMPs) to eliminate harmful microbes. We reported that the intermediate filament keratin 6a (K6a) is constitutively processed into antimicrobial fragments in corneal epithelial cells. In this study, we show that K6a network remodeling is a hos...

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Detalles Bibliográficos
Autores principales: Chan, Jonathan K.L., Yuen, Don, Too, Priscilla Hiu-Mei, Sun, Yan, Willard, Belinda, Man, David, Tam, Connie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800800/
https://www.ncbi.nlm.nih.gov/pubmed/29191848
http://dx.doi.org/10.1083/jcb.201704186

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