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Keratin 6a reorganization for ubiquitin–proteasomal processing is a direct antimicrobial response
Skin and mucosal epithelia deploy antimicrobial peptides (AMPs) to eliminate harmful microbes. We reported that the intermediate filament keratin 6a (K6a) is constitutively processed into antimicrobial fragments in corneal epithelial cells. In this study, we show that K6a network remodeling is a hos...
Autores principales: | Chan, Jonathan K.L., Yuen, Don, Too, Priscilla Hiu-Mei, Sun, Yan, Willard, Belinda, Man, David, Tam, Connie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800800/ https://www.ncbi.nlm.nih.gov/pubmed/29191848 http://dx.doi.org/10.1083/jcb.201704186 |
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