Cargando…
Inhibition of Mdmx (Mdm4) in vivo induces anti-obesity effects
Although cell-cycle arrest, senescence and apoptosis remain as major canonical activities of p53 in tumor suppression, the emerging role of p53 in metabolism has been a topic of great interest. Nevertheless, it is not completely understood how p53-mediated metabolic activities are regulated in vivo...
Autores principales: | Kon, Ning, Wang, Donglai, Li, Tongyuan, Jiang, Le, Qiang, Li, Gu, Wei |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800902/ https://www.ncbi.nlm.nih.gov/pubmed/29484110 http://dx.doi.org/10.18632/oncotarget.23837 |
Ejemplares similares
-
Benzimidazoles Downregulate Mdm2 and MdmX and Activate p53 in MdmX Overexpressing Tumor Cells
por: Mrkvová, Zuzana, et al.
Publicado: (2019) -
MDM4 (MDMX) and its Transcript Variants
por: Mancini, F, et al.
Publicado: (2009) -
Is MDMX the better target?
por: Kon, Ning, et al.
Publicado: (2018) -
Hinokiflavone Inhibits MDM2 Activity by Targeting the MDM2-MDMX RING Domain
por: Ilic, Viktoria K., et al.
Publicado: (2022) -
Role of Mdm2 and Mdmx in DNA repair
por: Eischen, Christine M.
Publicado: (2017)