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Evidence that PP2A activity is dispensable for spindle assembly checkpoint-dependent control of Cdk1

Progression through mitosis, the cell cycle phase deputed to segregate replicated chromosomes, is granted by a protein phosphorylation wave that follows an activation-inactivation cycle of cyclin B-dependent kinase (Cdk) 1, the major mitosis-promoting enzyme. To ensure correct chromosome segregation...

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Detalles Bibliográficos
Autores principales: Cervone, Nando, Monica, Rosa Della, Serpico, Angela Flavia, Vetrei, Cinzia, Scaraglio, Mario, Visconti, Roberta, Grieco, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800904/
https://www.ncbi.nlm.nih.gov/pubmed/29484112
http://dx.doi.org/10.18632/oncotarget.23329

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