Cargando…
Evidence that PP2A activity is dispensable for spindle assembly checkpoint-dependent control of Cdk1
Progression through mitosis, the cell cycle phase deputed to segregate replicated chromosomes, is granted by a protein phosphorylation wave that follows an activation-inactivation cycle of cyclin B-dependent kinase (Cdk) 1, the major mitosis-promoting enzyme. To ensure correct chromosome segregation...
Autores principales: | Cervone, Nando, Monica, Rosa Della, Serpico, Angela Flavia, Vetrei, Cinzia, Scaraglio, Mario, Visconti, Roberta, Grieco, Domenico |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800904/ https://www.ncbi.nlm.nih.gov/pubmed/29484112 http://dx.doi.org/10.18632/oncotarget.23329 |
Ejemplares similares
-
Fcp1 phosphatase controls Greatwall kinase to promote PP2A-B55 activation and mitotic progression
por: Della Monica, Rosa, et al.
Publicado: (2015) -
Recent advances in understanding the role of Cdk1 in the Spindle Assembly Checkpoint
por: Serpico, Angela Flavia, et al.
Publicado: (2020) -
Sustaining the spindle assembly checkpoint to improve cancer therapy
por: Visconti, Roberta, et al.
Publicado: (2015) -
Wee1 Rather Than Plk1 Is Inhibited by AZD1775 at Therapeutically Relevant Concentrations
por: Serpico, Angela Flavia, et al.
Publicado: (2019) -
On the assembly of the mitotic spindle, bistability and hysteresis
por: Serpico, Angela Flavia, et al.
Publicado: (2023)