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Novel mutational landscapes and expression signatures of lung squamous cell carcinoma

Lung squamous cell carcinoma (LUSC) is a major subtype of Non-Small Cell Lung Cancer. To increase our understanding of the LUSC pathobiology, we performed exome sequencing and RNA-seq in 16 murine carcinogen-induced LUSC tumors and 8 normal murine lung tissue samples. Additionally, we conducted sing...

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Detalles Bibliográficos
Autores principales: Xiong, Donghai, Pan, Jing, Yin, Yuxin, Jiang, Hui, Szabo, Eva, Lubet, Ronald A., Wang, Yian, You, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800913/
https://www.ncbi.nlm.nih.gov/pubmed/29484121
http://dx.doi.org/10.18632/oncotarget.23716