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Dual targeting of mitochondrial function and mTOR pathway as a therapeutic strategy for diffuse intrinsic pontine glioma
Diffuse Intrinsic Pontine Gliomas (DIPG) are the most devastating of all pediatric brain tumors. They mostly affect young children and, as there are no effective treatments, almost all patients with DIPG will die of their tumor within 12 months of diagnosis. A key feature of this devastating tumor i...
Autores principales: | Tsoli, Maria, Liu, Jie, Franshaw, Laura, Shen, Han, Cheng, Cecilia, Jung, MoonSun, Joshi, Swapna, Ehteda, Anahid, Khan, Aaminah, Montero-Carcabosso, Angel, Dilda, Pierre J., Hogg, Philip, Ziegler, David S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800923/ https://www.ncbi.nlm.nih.gov/pubmed/29484131 http://dx.doi.org/10.18632/oncotarget.24045 |
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