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Leptin receptor-expressing bone marrow stromal cells are myofibroblasts in primary myelofibrosis

Bone marrow fibrosis is a critical component of primary myelofibrosis (PMF). But the origin of myofibroblasts that drive fibrosis is unknown. Using genetic fate mapping we found that bone marrow Leptin receptor (Lepr) – expressing mesenchymal stromal lineage cells expanded extensively and were the f...

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Detalles Bibliográficos
Autores principales:	Decker, Matthew, Martinez-Morentin, Leticia, Wang, Guannan, Lee, Yeojin, Liu, Qingxue, Leslie, Juliana, Ding, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801040/ https://www.ncbi.nlm.nih.gov/pubmed/28481328 http://dx.doi.org/10.1038/ncb3530

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