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Critical Role of TGF-β and IL-2 Receptor Signaling in Foxp3 Induction by an Inhibitor of DNA Methylation

Under physiological conditions, CD4(+) regulatory T (Treg) cells expressing the transcription factor Foxp3 are generated in the thymus [thymus-derived Foxp3(+) Treg (tTregs) cells] and extrathymically at peripheral sites [peripherally induced Foxp3(+) Treg (pTreg) cell], and both developmental subse...

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Detalles Bibliográficos
Autores principales:	Freudenberg, Kristin, Lindner, Nadja, Dohnke, Sebastian, Garbe, Annette I., Schallenberg, Sonja, Kretschmer, Karsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801288/ https://www.ncbi.nlm.nih.gov/pubmed/29456534 http://dx.doi.org/10.3389/fimmu.2018.00125

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