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Synaptic E-I Balance Underlies Efficient Neural Coding
Both theoretical and experimental evidence indicate that synaptic excitation and inhibition in the cerebral cortex are well-balanced during the resting state and sensory processing. Here, we briefly summarize the evidence for how neural circuits are adjusted to achieve this balance. Then, we discuss...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801300/ https://www.ncbi.nlm.nih.gov/pubmed/29456491 http://dx.doi.org/10.3389/fnins.2018.00046 |
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author | Zhou, Shanglin Yu, Yuguo |
author_facet | Zhou, Shanglin Yu, Yuguo |
author_sort | Zhou, Shanglin |
collection | PubMed |
description | Both theoretical and experimental evidence indicate that synaptic excitation and inhibition in the cerebral cortex are well-balanced during the resting state and sensory processing. Here, we briefly summarize the evidence for how neural circuits are adjusted to achieve this balance. Then, we discuss how such excitatory and inhibitory balance shapes stimulus representation and information propagation, two basic functions of neural coding. We also point out the benefit of adopting such a balance during neural coding. We conclude that excitatory and inhibitory balance may be a fundamental mechanism underlying efficient coding. |
format | Online Article Text |
id | pubmed-5801300 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-58013002018-02-16 Synaptic E-I Balance Underlies Efficient Neural Coding Zhou, Shanglin Yu, Yuguo Front Neurosci Neuroscience Both theoretical and experimental evidence indicate that synaptic excitation and inhibition in the cerebral cortex are well-balanced during the resting state and sensory processing. Here, we briefly summarize the evidence for how neural circuits are adjusted to achieve this balance. Then, we discuss how such excitatory and inhibitory balance shapes stimulus representation and information propagation, two basic functions of neural coding. We also point out the benefit of adopting such a balance during neural coding. We conclude that excitatory and inhibitory balance may be a fundamental mechanism underlying efficient coding. Frontiers Media S.A. 2018-02-02 /pmc/articles/PMC5801300/ /pubmed/29456491 http://dx.doi.org/10.3389/fnins.2018.00046 Text en Copyright © 2018 Zhou and Yu. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neuroscience Zhou, Shanglin Yu, Yuguo Synaptic E-I Balance Underlies Efficient Neural Coding |
title | Synaptic E-I Balance Underlies Efficient Neural Coding |
title_full | Synaptic E-I Balance Underlies Efficient Neural Coding |
title_fullStr | Synaptic E-I Balance Underlies Efficient Neural Coding |
title_full_unstemmed | Synaptic E-I Balance Underlies Efficient Neural Coding |
title_short | Synaptic E-I Balance Underlies Efficient Neural Coding |
title_sort | synaptic e-i balance underlies efficient neural coding |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801300/ https://www.ncbi.nlm.nih.gov/pubmed/29456491 http://dx.doi.org/10.3389/fnins.2018.00046 |
work_keys_str_mv | AT zhoushanglin synapticeibalanceunderliesefficientneuralcoding AT yuyuguo synapticeibalanceunderliesefficientneuralcoding |