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Mathematical Modeling of Protein Misfolding Mechanisms in Neurological Diseases: A Historical Overview
Protein misfolding refers to a process where proteins become structurally abnormal and lose their specific 3-dimensional spatial configuration. The histopathological presence of misfolded protein (MP) aggregates has been associated as the primary evidence of multiple neurological diseases, including...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801313/ https://www.ncbi.nlm.nih.gov/pubmed/29456521 http://dx.doi.org/10.3389/fneur.2018.00037 |