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Zika Virus Alters DNA Methylation of Neural Genes in an Organoid Model of the Developing Human Brain
Zika virus (ZIKV) infection during early pregnancy can cause microcephaly and associated defects at birth, but whether it can induce neurologic sequelae that appear later in life remains unclear. Using a model of the developing brain based on embryonic stem cell-derived brain organoids, we studied t...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Microbiology
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801341/ https://www.ncbi.nlm.nih.gov/pubmed/29435496 http://dx.doi.org/10.1128/mSystems.00219-17 |