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Dissection of Signaling Events Downstream of the c-Mpl Receptor in Murine Hematopoietic Stem Cells Via Motif-Engineered Chimeric Receptors

Hematopoietic stem cells (HSCs) are a valuable resource in transplantation medicine. Cytokines are often used to culture HSCs aiming at better clinical outcomes through enhancement of HSC reconstitution capability. Roles for each signal molecule downstream of receptors in HSCs, however, remain puzzl...

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Detalles Bibliográficos
Autores principales: Saka, Koichiro, Lai, Chen-Yi, Nojima, Masanori, Kawahara, Masahiro, Otsu, Makoto, Nakauchi, Hiromitsu, Nagamune, Teruyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801400/
https://www.ncbi.nlm.nih.gov/pubmed/28948469
http://dx.doi.org/10.1007/s12015-017-9768-7