Cargando…
Administration of Ketamine Causes Autophagy and Apoptosis in the Rat Fetal Hippocampus and in PC12 Cells
Drug abuse during pregnancy is a serious problem. Like alcohol, anticonvulsants, sedatives, and anesthetics, such as ketamine, can pass through the placental barrier and affect the growing fetus. However, the mechanism by which ketamine causes damage to fetal rats is not well understood. Therefore,...
Autores principales: | Li, Xinran, Li, Yanan, Zhao, Jinghua, Li, Lina, Wang, Yuxin, Zhang, Yiming, Li, Yue, Chen, Yu, Liu, Wenhan, Gao, Li |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801406/ https://www.ncbi.nlm.nih.gov/pubmed/29456493 http://dx.doi.org/10.3389/fncel.2018.00021 |
Ejemplares similares
-
Ketamine administered pregnant rats impair learning and memory in offspring via the CREB pathway
por: Li, Xinran, et al.
Publicado: (2017) -
Long-term neurocognitive dysfunction in offspring via NGF/ ERK/CREB signaling pathway caused by ketamine exposure during the second trimester of pregnancy in rats
por: Li, Yanan, et al.
Publicado: (2017) -
Molecular mechanisms of the sedation and analgesia induced by xylazine on
Wistar rats and PC12 cell
por: Zhao, Jinghua, et al.
Publicado: (2019) -
Effects of Ketamine on Learning and Memory in the Hippocampus of Rats through ERK, CREB, and Arc
por: Shi, Mingxian, et al.
Publicado: (2020) -
Alcohol amplifies ketamine-induced apoptosis in primary cultured cortical neurons and PC12 cells through down-regulating CREB-related signaling pathways
por: Zuo, Daiying, et al.
Publicado: (2017)