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Repair or prosthesis insertion in ischemic mitral regurgitation: Two faces of the same medal

OBJECTIVE: The proper treatment of chronic ischemic mitral regurgitation (CIMR) is still under evaluation. The different role of mitral valve repair (MVr) or mitral valve prosthesis insertion (MVPI) is still not defined. METHODS: From May 2009 to December 2011 167 patients with ejection fraction (EF...

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Autores principales: Calafiore, Antonio Maria, Iacò, Angela Lorena, Clemente, Daniela, Refaie, Reda, Romano, Silvio, Asif, Mahmood, Penco, Maria, Di Mauro, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801432/
https://www.ncbi.nlm.nih.gov/pubmed/29450167
http://dx.doi.org/10.1016/j.ijchv.2014.02.002
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author Calafiore, Antonio Maria
Iacò, Angela Lorena
Clemente, Daniela
Refaie, Reda
Romano, Silvio
Asif, Mahmood
Penco, Maria
Di Mauro, Michele
author_facet Calafiore, Antonio Maria
Iacò, Angela Lorena
Clemente, Daniela
Refaie, Reda
Romano, Silvio
Asif, Mahmood
Penco, Maria
Di Mauro, Michele
author_sort Calafiore, Antonio Maria
collection PubMed
description OBJECTIVE: The proper treatment of chronic ischemic mitral regurgitation (CIMR) is still under evaluation. The different role of mitral valve repair (MVr) or mitral valve prosthesis insertion (MVPI) is still not defined. METHODS: From May 2009 to December 2011 167 patients with ejection fraction (EF) ≤ 40% had MV surgery for CIMR, MVr in 135 (80.8%) and MVPI in 32 (19.2%). Indication to MVPI was a MV coaptation depth > 10 mm. EF was lower (26 ± 7 vs 32 ± 6, p = 0.0000) in MVPI, whereas MR grade (3.6 ± 0.8 vs 2.7 ± 0.9, p = 0.0000), left ventricle dimensions (end diastolic, LVEDD, 62 ± 7 vs 57 ± 6 mm, p = 0.0001; end systolic, LVESD, 49 ± 8 vs 44 ± 8 mm, p = 0.0018), systolic pulmonary artery pressure (51 ± 22 vs 41 ± 16 mm Hg, p = 0.0037) and NYHA Class (3.6 ± 0.5 vs 2.8 ± 0.6, p = 0.0000) were higher. RESULTS: In-hospital mortality was similar (3.1 vs 3.7%) as well as 3-year survival (86 ± 6 vs 88 ± 4) and survival in NYHA Class I/II (80 ± 5 vs 83 ± 4). One hundred thirty nine patients had an echocardiographic evaluation after a minimum of 4 months (13 ± 8). EF rose significantly in both groups (from 26 ± 7% to 30 ± 4%, p = 0.0122, and from 32 ± 6% to 35 ± 8%, p = 0.0018). LVESD reduced significantly in both groups (from 49 ± 8 to 43 ± 9 mm, p = 0.0109, and from 44 ± 8 to 41 ± 7 mm, p = 0.0033). MR grade was significantly lower in patients who had MVPI (0.1 ± 0.2 vs 0.3 ± 0.3, p = 0.0011). CONCLUSIONS: With appropriate indications, MVPI is a safe procedure which provides similar results to MVr with lower MR return, even if addressed to patients with worse preoperative parameters.
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spelling pubmed-58014322018-02-15 Repair or prosthesis insertion in ischemic mitral regurgitation: Two faces of the same medal Calafiore, Antonio Maria Iacò, Angela Lorena Clemente, Daniela Refaie, Reda Romano, Silvio Asif, Mahmood Penco, Maria Di Mauro, Michele Int J Cardiol Heart Vessel Original Article OBJECTIVE: The proper treatment of chronic ischemic mitral regurgitation (CIMR) is still under evaluation. The different role of mitral valve repair (MVr) or mitral valve prosthesis insertion (MVPI) is still not defined. METHODS: From May 2009 to December 2011 167 patients with ejection fraction (EF) ≤ 40% had MV surgery for CIMR, MVr in 135 (80.8%) and MVPI in 32 (19.2%). Indication to MVPI was a MV coaptation depth > 10 mm. EF was lower (26 ± 7 vs 32 ± 6, p = 0.0000) in MVPI, whereas MR grade (3.6 ± 0.8 vs 2.7 ± 0.9, p = 0.0000), left ventricle dimensions (end diastolic, LVEDD, 62 ± 7 vs 57 ± 6 mm, p = 0.0001; end systolic, LVESD, 49 ± 8 vs 44 ± 8 mm, p = 0.0018), systolic pulmonary artery pressure (51 ± 22 vs 41 ± 16 mm Hg, p = 0.0037) and NYHA Class (3.6 ± 0.5 vs 2.8 ± 0.6, p = 0.0000) were higher. RESULTS: In-hospital mortality was similar (3.1 vs 3.7%) as well as 3-year survival (86 ± 6 vs 88 ± 4) and survival in NYHA Class I/II (80 ± 5 vs 83 ± 4). One hundred thirty nine patients had an echocardiographic evaluation after a minimum of 4 months (13 ± 8). EF rose significantly in both groups (from 26 ± 7% to 30 ± 4%, p = 0.0122, and from 32 ± 6% to 35 ± 8%, p = 0.0018). LVESD reduced significantly in both groups (from 49 ± 8 to 43 ± 9 mm, p = 0.0109, and from 44 ± 8 to 41 ± 7 mm, p = 0.0033). MR grade was significantly lower in patients who had MVPI (0.1 ± 0.2 vs 0.3 ± 0.3, p = 0.0011). CONCLUSIONS: With appropriate indications, MVPI is a safe procedure which provides similar results to MVr with lower MR return, even if addressed to patients with worse preoperative parameters. Elsevier 2014-03-03 /pmc/articles/PMC5801432/ /pubmed/29450167 http://dx.doi.org/10.1016/j.ijchv.2014.02.002 Text en © 2014 The Authors http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
spellingShingle Original Article
Calafiore, Antonio Maria
Iacò, Angela Lorena
Clemente, Daniela
Refaie, Reda
Romano, Silvio
Asif, Mahmood
Penco, Maria
Di Mauro, Michele
Repair or prosthesis insertion in ischemic mitral regurgitation: Two faces of the same medal
title Repair or prosthesis insertion in ischemic mitral regurgitation: Two faces of the same medal
title_full Repair or prosthesis insertion in ischemic mitral regurgitation: Two faces of the same medal
title_fullStr Repair or prosthesis insertion in ischemic mitral regurgitation: Two faces of the same medal
title_full_unstemmed Repair or prosthesis insertion in ischemic mitral regurgitation: Two faces of the same medal
title_short Repair or prosthesis insertion in ischemic mitral regurgitation: Two faces of the same medal
title_sort repair or prosthesis insertion in ischemic mitral regurgitation: two faces of the same medal
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801432/
https://www.ncbi.nlm.nih.gov/pubmed/29450167
http://dx.doi.org/10.1016/j.ijchv.2014.02.002
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