Cargando…
Repair or prosthesis insertion in ischemic mitral regurgitation: Two faces of the same medal
OBJECTIVE: The proper treatment of chronic ischemic mitral regurgitation (CIMR) is still under evaluation. The different role of mitral valve repair (MVr) or mitral valve prosthesis insertion (MVPI) is still not defined. METHODS: From May 2009 to December 2011 167 patients with ejection fraction (EF...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801432/ https://www.ncbi.nlm.nih.gov/pubmed/29450167 http://dx.doi.org/10.1016/j.ijchv.2014.02.002 |
_version_ | 1783298349503348736 |
---|---|
author | Calafiore, Antonio Maria Iacò, Angela Lorena Clemente, Daniela Refaie, Reda Romano, Silvio Asif, Mahmood Penco, Maria Di Mauro, Michele |
author_facet | Calafiore, Antonio Maria Iacò, Angela Lorena Clemente, Daniela Refaie, Reda Romano, Silvio Asif, Mahmood Penco, Maria Di Mauro, Michele |
author_sort | Calafiore, Antonio Maria |
collection | PubMed |
description | OBJECTIVE: The proper treatment of chronic ischemic mitral regurgitation (CIMR) is still under evaluation. The different role of mitral valve repair (MVr) or mitral valve prosthesis insertion (MVPI) is still not defined. METHODS: From May 2009 to December 2011 167 patients with ejection fraction (EF) ≤ 40% had MV surgery for CIMR, MVr in 135 (80.8%) and MVPI in 32 (19.2%). Indication to MVPI was a MV coaptation depth > 10 mm. EF was lower (26 ± 7 vs 32 ± 6, p = 0.0000) in MVPI, whereas MR grade (3.6 ± 0.8 vs 2.7 ± 0.9, p = 0.0000), left ventricle dimensions (end diastolic, LVEDD, 62 ± 7 vs 57 ± 6 mm, p = 0.0001; end systolic, LVESD, 49 ± 8 vs 44 ± 8 mm, p = 0.0018), systolic pulmonary artery pressure (51 ± 22 vs 41 ± 16 mm Hg, p = 0.0037) and NYHA Class (3.6 ± 0.5 vs 2.8 ± 0.6, p = 0.0000) were higher. RESULTS: In-hospital mortality was similar (3.1 vs 3.7%) as well as 3-year survival (86 ± 6 vs 88 ± 4) and survival in NYHA Class I/II (80 ± 5 vs 83 ± 4). One hundred thirty nine patients had an echocardiographic evaluation after a minimum of 4 months (13 ± 8). EF rose significantly in both groups (from 26 ± 7% to 30 ± 4%, p = 0.0122, and from 32 ± 6% to 35 ± 8%, p = 0.0018). LVESD reduced significantly in both groups (from 49 ± 8 to 43 ± 9 mm, p = 0.0109, and from 44 ± 8 to 41 ± 7 mm, p = 0.0033). MR grade was significantly lower in patients who had MVPI (0.1 ± 0.2 vs 0.3 ± 0.3, p = 0.0011). CONCLUSIONS: With appropriate indications, MVPI is a safe procedure which provides similar results to MVr with lower MR return, even if addressed to patients with worse preoperative parameters. |
format | Online Article Text |
id | pubmed-5801432 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-58014322018-02-15 Repair or prosthesis insertion in ischemic mitral regurgitation: Two faces of the same medal Calafiore, Antonio Maria Iacò, Angela Lorena Clemente, Daniela Refaie, Reda Romano, Silvio Asif, Mahmood Penco, Maria Di Mauro, Michele Int J Cardiol Heart Vessel Original Article OBJECTIVE: The proper treatment of chronic ischemic mitral regurgitation (CIMR) is still under evaluation. The different role of mitral valve repair (MVr) or mitral valve prosthesis insertion (MVPI) is still not defined. METHODS: From May 2009 to December 2011 167 patients with ejection fraction (EF) ≤ 40% had MV surgery for CIMR, MVr in 135 (80.8%) and MVPI in 32 (19.2%). Indication to MVPI was a MV coaptation depth > 10 mm. EF was lower (26 ± 7 vs 32 ± 6, p = 0.0000) in MVPI, whereas MR grade (3.6 ± 0.8 vs 2.7 ± 0.9, p = 0.0000), left ventricle dimensions (end diastolic, LVEDD, 62 ± 7 vs 57 ± 6 mm, p = 0.0001; end systolic, LVESD, 49 ± 8 vs 44 ± 8 mm, p = 0.0018), systolic pulmonary artery pressure (51 ± 22 vs 41 ± 16 mm Hg, p = 0.0037) and NYHA Class (3.6 ± 0.5 vs 2.8 ± 0.6, p = 0.0000) were higher. RESULTS: In-hospital mortality was similar (3.1 vs 3.7%) as well as 3-year survival (86 ± 6 vs 88 ± 4) and survival in NYHA Class I/II (80 ± 5 vs 83 ± 4). One hundred thirty nine patients had an echocardiographic evaluation after a minimum of 4 months (13 ± 8). EF rose significantly in both groups (from 26 ± 7% to 30 ± 4%, p = 0.0122, and from 32 ± 6% to 35 ± 8%, p = 0.0018). LVESD reduced significantly in both groups (from 49 ± 8 to 43 ± 9 mm, p = 0.0109, and from 44 ± 8 to 41 ± 7 mm, p = 0.0033). MR grade was significantly lower in patients who had MVPI (0.1 ± 0.2 vs 0.3 ± 0.3, p = 0.0011). CONCLUSIONS: With appropriate indications, MVPI is a safe procedure which provides similar results to MVr with lower MR return, even if addressed to patients with worse preoperative parameters. Elsevier 2014-03-03 /pmc/articles/PMC5801432/ /pubmed/29450167 http://dx.doi.org/10.1016/j.ijchv.2014.02.002 Text en © 2014 The Authors http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/). |
spellingShingle | Original Article Calafiore, Antonio Maria Iacò, Angela Lorena Clemente, Daniela Refaie, Reda Romano, Silvio Asif, Mahmood Penco, Maria Di Mauro, Michele Repair or prosthesis insertion in ischemic mitral regurgitation: Two faces of the same medal |
title | Repair or prosthesis insertion in ischemic mitral regurgitation: Two faces of the same medal |
title_full | Repair or prosthesis insertion in ischemic mitral regurgitation: Two faces of the same medal |
title_fullStr | Repair or prosthesis insertion in ischemic mitral regurgitation: Two faces of the same medal |
title_full_unstemmed | Repair or prosthesis insertion in ischemic mitral regurgitation: Two faces of the same medal |
title_short | Repair or prosthesis insertion in ischemic mitral regurgitation: Two faces of the same medal |
title_sort | repair or prosthesis insertion in ischemic mitral regurgitation: two faces of the same medal |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801432/ https://www.ncbi.nlm.nih.gov/pubmed/29450167 http://dx.doi.org/10.1016/j.ijchv.2014.02.002 |
work_keys_str_mv | AT calafioreantoniomaria repairorprosthesisinsertioninischemicmitralregurgitationtwofacesofthesamemedal AT iacoangelalorena repairorprosthesisinsertioninischemicmitralregurgitationtwofacesofthesamemedal AT clementedaniela repairorprosthesisinsertioninischemicmitralregurgitationtwofacesofthesamemedal AT refaiereda repairorprosthesisinsertioninischemicmitralregurgitationtwofacesofthesamemedal AT romanosilvio repairorprosthesisinsertioninischemicmitralregurgitationtwofacesofthesamemedal AT asifmahmood repairorprosthesisinsertioninischemicmitralregurgitationtwofacesofthesamemedal AT pencomaria repairorprosthesisinsertioninischemicmitralregurgitationtwofacesofthesamemedal AT dimauromichele repairorprosthesisinsertioninischemicmitralregurgitationtwofacesofthesamemedal |