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Nef Secretion into Extracellular Vesicles or Exosomes Is Conserved across Human and Simian Immunodeficiency Viruses

Extracellular vesicles (EVs) or exosomes have been implicated in the pathophysiology of infections and cancer. The negative regulatory factor (Nef) encoded by simian immunodeficiency virus (SIV) and human immunodeficiency virus (HIV) plays a critical role in the progression to AIDS and impairs endos...

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Detalles Bibliográficos
Autores principales: McNamara, Ryan P., Costantini, Lindsey M., Myers, T. Alix, Schouest, Blake, Maness, Nicholas J., Griffith, Jack D., Damania, Blossom A., MacLean, Andrew G., Dittmer, Dirk P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801467/
https://www.ncbi.nlm.nih.gov/pubmed/29437924
http://dx.doi.org/10.1128/mBio.02344-17

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