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Nef Secretion into Extracellular Vesicles or Exosomes Is Conserved across Human and Simian Immunodeficiency Viruses
Extracellular vesicles (EVs) or exosomes have been implicated in the pathophysiology of infections and cancer. The negative regulatory factor (Nef) encoded by simian immunodeficiency virus (SIV) and human immunodeficiency virus (HIV) plays a critical role in the progression to AIDS and impairs endos...
Autores principales: | McNamara, Ryan P., Costantini, Lindsey M., Myers, T. Alix, Schouest, Blake, Maness, Nicholas J., Griffith, Jack D., Damania, Blossom A., MacLean, Andrew G., Dittmer, Dirk P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801467/ https://www.ncbi.nlm.nih.gov/pubmed/29437924 http://dx.doi.org/10.1128/mBio.02344-17 |
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