SEMA3C drives cancer growth by transactivating multiple receptor tyrosine kinases via Plexin B1

Growth factor receptor tyrosine kinase (RTK) pathway activation is a key mechanism for mediating cancer growth, survival, and treatment resistance. Cognate ligands play crucial roles in autocrine or paracrine stimulation of these RTK pathways. Here, we show SEMA3C drives activation of multiple RTKs...

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Detalles Bibliográficos
Autores principales: Peacock, James W, Takeuchi, Ario, Hayashi, Norihiro, Liu, Liangliang, Tam, Kevin J, Al Nakouzi, Nader, Khazamipour, Nastaran, Tombe, Tabitha, Dejima, Takashi, Lee, Kevin CK, Shiota, Masaki, Thaper, Daksh, Lee, Wilson CW, Hui, Daniel HF, Kuruma, Hidetoshi, Ivanova, Larissa, Yenki, Parvin, Jiao, Ivy ZF, Khosravi, Shahram, Mui, Alice L‐F, Fazli, Ladan, Zoubeidi, Amina, Daugaard, Mads, Gleave, Martin E, Ong, Christopher J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801490/
https://www.ncbi.nlm.nih.gov/pubmed/29348142
http://dx.doi.org/10.15252/emmm.201707689

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