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The immunoproteasome‐specific inhibitor ONX 0914 reverses susceptibility to acute viral myocarditis

Severe heart pathology upon virus infection is closely associated with the immunological equipment of the host. Since there is no specific treatment available, current research focuses on identifying new drug targets to positively modulate predisposing immune factors. Utilizing a murine model with h...

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Detalles Bibliográficos
Autores principales: Althof, Nadine, Goetzke, Carl Christoph, Kespohl, Meike, Voss, Karolin, Heuser, Arnd, Pinkert, Sandra, Kaya, Ziya, Klingel, Karin, Beling, Antje
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801517/
https://www.ncbi.nlm.nih.gov/pubmed/29295868
http://dx.doi.org/10.15252/emmm.201708089