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The Art of War: harnessing the epigenome against cancer
Histone chaperones are indispensable regulators of chromatin structure and function. Recent work has shown that they are frequently mis-regulated in cancer, which can have profound consequences on tumor growth and survival. Here, we focus on chaperones for the essential H3 histone variants H3.3 and...
Autores principales: | Nye, Jonathan, Melters, Daniël P., Dalal, Yamini |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801563/ https://www.ncbi.nlm.nih.gov/pubmed/29479426 http://dx.doi.org/10.12688/f1000research.12833.1 |
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