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Structural Variation of Chondroitin Sulfate Chains Contributes to the Molecular Heterogeneity of Perineuronal Nets

Aggrecan, a chondroitin sulfate (CS) proteoglycan, forms lattice-like extracellular matrix structures called perineuronal nets (PNNs). Neocortical PNNs primarily ensheath parvalbumin-expressing inhibitory neurons (parvalbumin, PV cells) late in brain development. Emerging evidence indicates that PNN...

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Detalles Bibliográficos
Autores principales: Miyata, Shinji, Nadanaka, Satomi, Igarashi, Michihiro, Kitagawa, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801575/
https://www.ncbi.nlm.nih.gov/pubmed/29456495
http://dx.doi.org/10.3389/fnint.2018.00003