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Prevalence and Severity of Sleep Disturbances among Patients with Early Breast Cancer

CONTEXT: Data regarding health-related quality of life in breast cancer patients in the Middle East are limited with fatigue and sleep disturbance being the most distressing symptoms reported by patients treated for early breast cancer. AIMS: The aim of this study was to examine the prevalence and i...

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Autores principales: Fakih, Rami, Rahal, Mahmoud, Hilal, Lara, Hamieh, Lana, Dany, Mohammed, Karam, Simone, Shehab, Latifa, El Saghir, Nagi S, Tfayli, Arafat, Salem, Ziad, Assi, Hazem, Temraz, Sally, Shamseddine, Ali, Mukherji, Deborah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801627/
https://www.ncbi.nlm.nih.gov/pubmed/29440804
http://dx.doi.org/10.4103/IJPC.IJPC_137_17
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author Fakih, Rami
Rahal, Mahmoud
Hilal, Lara
Hamieh, Lana
Dany, Mohammed
Karam, Simone
Shehab, Latifa
El Saghir, Nagi S
Tfayli, Arafat
Salem, Ziad
Assi, Hazem
Temraz, Sally
Shamseddine, Ali
Mukherji, Deborah
author_facet Fakih, Rami
Rahal, Mahmoud
Hilal, Lara
Hamieh, Lana
Dany, Mohammed
Karam, Simone
Shehab, Latifa
El Saghir, Nagi S
Tfayli, Arafat
Salem, Ziad
Assi, Hazem
Temraz, Sally
Shamseddine, Ali
Mukherji, Deborah
author_sort Fakih, Rami
collection PubMed
description CONTEXT: Data regarding health-related quality of life in breast cancer patients in the Middle East are limited with fatigue and sleep disturbance being the most distressing symptoms reported by patients treated for early breast cancer. AIMS: The aim of this study was to examine the prevalence and incidence of insomnia among patients with early-stage breast cancer patients treated with chemotherapy. SUBJECTS AND METHODS: This was a prospective cohort study. We enrolled patients with stage I-III breast cancer patients treated with chemotherapy at the American University of Beirut Medical Center. At three different time points (prior to, during, and following chemotherapy), we assessed the severity of sleep disturbances using the Pittsburgh Sleep Quality Index and the Insomnia Severity Index. The Institution Review Board approved the study. RESULTS: Fifty-two patients were recruited. There was a significant increase in sleep disturbances during chemotherapy which improved to below baseline levels on completion of therapy. Prior to chemotherapy, 36% of patients reported poor sleep versus 58% during chemotherapy. The percentage of patients reporting clinical insomnia rose from 11% pretreatment to 36% during chemotherapy reflecting a significant symptomatic burden that is poorly documented and managed in routine clinical practice. CONCLUSIONS: Patients with nonmetastatic breast cancer experience an increase in sleep disturbances during the treatment phase. Physicians should be aware of the need to routinely screen for sleep disturbance in breast cancer patients undergoing chemotherapy.
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spelling pubmed-58016272018-02-13 Prevalence and Severity of Sleep Disturbances among Patients with Early Breast Cancer Fakih, Rami Rahal, Mahmoud Hilal, Lara Hamieh, Lana Dany, Mohammed Karam, Simone Shehab, Latifa El Saghir, Nagi S Tfayli, Arafat Salem, Ziad Assi, Hazem Temraz, Sally Shamseddine, Ali Mukherji, Deborah Indian J Palliat Care Original Article CONTEXT: Data regarding health-related quality of life in breast cancer patients in the Middle East are limited with fatigue and sleep disturbance being the most distressing symptoms reported by patients treated for early breast cancer. AIMS: The aim of this study was to examine the prevalence and incidence of insomnia among patients with early-stage breast cancer patients treated with chemotherapy. SUBJECTS AND METHODS: This was a prospective cohort study. We enrolled patients with stage I-III breast cancer patients treated with chemotherapy at the American University of Beirut Medical Center. At three different time points (prior to, during, and following chemotherapy), we assessed the severity of sleep disturbances using the Pittsburgh Sleep Quality Index and the Insomnia Severity Index. The Institution Review Board approved the study. RESULTS: Fifty-two patients were recruited. There was a significant increase in sleep disturbances during chemotherapy which improved to below baseline levels on completion of therapy. Prior to chemotherapy, 36% of patients reported poor sleep versus 58% during chemotherapy. The percentage of patients reporting clinical insomnia rose from 11% pretreatment to 36% during chemotherapy reflecting a significant symptomatic burden that is poorly documented and managed in routine clinical practice. CONCLUSIONS: Patients with nonmetastatic breast cancer experience an increase in sleep disturbances during the treatment phase. Physicians should be aware of the need to routinely screen for sleep disturbance in breast cancer patients undergoing chemotherapy. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC5801627/ /pubmed/29440804 http://dx.doi.org/10.4103/IJPC.IJPC_137_17 Text en Copyright: © 2018 Indian Journal of Palliative Care http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Fakih, Rami
Rahal, Mahmoud
Hilal, Lara
Hamieh, Lana
Dany, Mohammed
Karam, Simone
Shehab, Latifa
El Saghir, Nagi S
Tfayli, Arafat
Salem, Ziad
Assi, Hazem
Temraz, Sally
Shamseddine, Ali
Mukherji, Deborah
Prevalence and Severity of Sleep Disturbances among Patients with Early Breast Cancer
title Prevalence and Severity of Sleep Disturbances among Patients with Early Breast Cancer
title_full Prevalence and Severity of Sleep Disturbances among Patients with Early Breast Cancer
title_fullStr Prevalence and Severity of Sleep Disturbances among Patients with Early Breast Cancer
title_full_unstemmed Prevalence and Severity of Sleep Disturbances among Patients with Early Breast Cancer
title_short Prevalence and Severity of Sleep Disturbances among Patients with Early Breast Cancer
title_sort prevalence and severity of sleep disturbances among patients with early breast cancer
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801627/
https://www.ncbi.nlm.nih.gov/pubmed/29440804
http://dx.doi.org/10.4103/IJPC.IJPC_137_17
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