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The UDP-glucose ceramide glycosyltransferase (UGCG) and the link to multidrug resistance protein 1 (MDR1)

The UDP-glucose ceramide glycosyltransferase (UGCG) is a key enzyme in the sphingolipid metabolism by generating glucosylceramide (GlcCer), the precursor for all glycosphingolipids (GSL), which are essential for proper cell function. Interestingly, the UGCG is also overexpressed in several cancer ty...

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Detalles Bibliográficos
Autores principales:	Wegner, Marthe-Susanna, Gruber, Lisa, Mattjus, Peter, Geisslinger, Gerd, Grösch, Sabine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Debate
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801679/ https://www.ncbi.nlm.nih.gov/pubmed/29409484 http://dx.doi.org/10.1186/s12885-018-4084-4

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