Neoadjuvant chemoradiotherapy plus surgery versus active surveillance for oesophageal cancer: a stepped-wedge cluster randomised trial

BACKGROUND: Neoadjuvant chemoradiotherapy (nCRT) plus surgery is a standard treatment for locally advanced oesophageal cancer. With this treatment, 29% of patients have a pathologically complete response in the resection specimen. This provides the rationale for investigating an active surveillance...

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Detalles Bibliográficos
Autores principales: Noordman, Bo Jan, Wijnhoven, Bas P. L., Lagarde, Sjoerd M., Boonstra, Jurjen J., Coene, Peter Paul L. O., Dekker, Jan Willem T., Doukas, Michael, van der Gaast, Ate, Heisterkamp, Joos, Kouwenhoven, Ewout A., Nieuwenhuijzen, Grard A. P., Pierie, Jean-Pierre E. N., Rosman, Camiel, van Sandick, Johanna W., van der Sangen, Maurice J. C., Sosef, Meindert N., Spaander, Manon C. W., Valkema, Roelf, van der Zaag, Edwin S., Steyerberg, Ewout W., van Lanschot, J. Jan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801846/
https://www.ncbi.nlm.nih.gov/pubmed/29409469
http://dx.doi.org/10.1186/s12885-018-4034-1

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