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Bcl-2 overexpression reduces cisplatin cytotoxicity by decreasing ER-mitochondrial Ca(2+) signaling in SKOV3 cells

Recent studies have revealed that a small amount of cisplatin can penetrate into the nucleus and induce intranuclear DNA damage. Specifically, most cisplatin accumulates in and stresses different organelles, including mitochondria, endoplasmic reticulum (ER) and the cytosol, where apoptosis signalin...

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Detalles Bibliográficos
Autores principales:	Xu, Lu, Xie, Qi, Qi, Ling, Wang, Chunyan, Xu, Na, Liu, Weimin, Yu, Yang, Li, Songyan, Xu, Ye
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802038/ https://www.ncbi.nlm.nih.gov/pubmed/29286126 http://dx.doi.org/10.3892/or.2017.6164

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