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Exploring the potential of 3D Zernike descriptors and SVM for protein–protein interface prediction

BACKGROUND: The correct determination of protein–protein interaction interfaces is important for understanding disease mechanisms and for rational drug design. To date, several computational methods for the prediction of protein interfaces have been developed, but the interface prediction problem is...

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Detalles Bibliográficos
Autores principales: Daberdaku, Sebastian, Ferrari, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802066/
https://www.ncbi.nlm.nih.gov/pubmed/29409446
http://dx.doi.org/10.1186/s12859-018-2043-3