Cargando…

Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer’s disease (DELCODE)

BACKGROUND: Deep phenotyping and longitudinal assessment of predementia at-risk states of Alzheimer’s disease (AD) are required to define populations and outcomes for dementia prevention trials. Subjective cognitive decline (SCD) is a pre-mild cognitive impairment (pre-MCI) at-risk state of dementia...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jessen, Frank, Spottke, Annika, Boecker, Henning, Brosseron, Frederic, Buerger, Katharina, Catak, Cihan, Fliessbach, Klaus, Franke, Christiana, Fuentes, Manuel, Heneka, Michael T., Janowitz, Daniel, Kilimann, Ingo, Laske, Christoph, Menne, Felix, Nestor, Peter, Peters, Oliver, Priller, Josef, Pross, Verena, Ramirez, Alfredo, Schneider, Anja, Speck, Oliver, Spruth, Eike Jakob, Teipel, Stefan, Vukovich, Ruth, Westerteicher, Christine, Wiltfang, Jens, Wolfsgruber, Steffen, Wagner, Michael, Düzel, Emrah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5802096/ https://www.ncbi.nlm.nih.gov/pubmed/29415768 http://dx.doi.org/10.1186/s13195-017-0314-2

Ejemplares similares

Tau plasma levels in subjective cognitive decline: Results from the DELCODE study
por: Müller, Stephan, et al.
Publicado: (2017)

Which features of subjective cognitive decline are related to amyloid pathology? Findings from the DELCODE study
por: Miebach, Lisa, et al.
Publicado: (2019)

Neuropsychiatric symptoms in at-risk groups for AD dementia and their association with worry and AD biomarkers—results from the DELCODE study
por: Sannemann, Lena, et al.
Publicado: (2020)

Serum IL-6, sAXL, and YKL-40 as systemic correlates of reduced brain structure and function in Alzheimer’s disease: results from the DELCODE study
por: Brosseron, Frederic, et al.
Publicado: (2023)

Multicenter Tract-Based Analysis of Microstructural Lesions within the Alzheimer’s Disease Spectrum: Association with Amyloid Pathology and Diagnostic Usefulness
por: Teipel, Stefan J., et al.
Publicado: (2019)

Memorability of photographs in subjective cognitive decline and mild cognitive impairment: Implications for cognitive assessment
por: Bainbridge, Wilma A., et al.
Publicado: (2019)

Hippocampal and Hippocampal-Subfield Volumes From Early-Onset Major Depression and Bipolar Disorder to Cognitive Decline
por: Hansen, Niels, et al.
Publicado: (2021)

CSF total tau levels are associated with hippocampal novelty irrespective of hippocampal volume
por: Düzel, Emrah, et al.
Publicado: (2018)

Dietary patterns are related to cognitive functioning in elderly enriched with individuals at increased risk for Alzheimer’s disease
por: Wesselman, L. M. P., et al.
Publicado: (2020)

Multimodal MRI analysis of basal forebrain structure and function across the Alzheimer’s disease spectrum
por: Herdick, Meret, et al.
Publicado: (2020)

Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer’s disease
por: Franzmeier, Nicolai, et al.
Publicado: (2018)

Relevance of Minor Neuropsychological Deficits in Patients With Subjective Cognitive Decline
por: Stark, Melina, et al.
Publicado: (2023)

Cognitive Trajectories in Preclinical and Prodromal Alzheimer’s Disease Related to Amyloid Status and Brain Atrophy: A Bayesian Approach
por: Teipel, Stefan J, et al.
Publicado: (2023)

Brain reserve contributes to distinguishing preclinical Alzheimer’s stages 1 and 2
por: Yildirim, Zerrin, et al.
Publicado: (2023)

Exploring the ATN classification system using brain morphology
por: Heinzinger, Nils, et al.
Publicado: (2023)

Improving 3D convolutional neural network comprehensibility via interactive visualization of relevance maps: evaluation in Alzheimer’s disease
por: Dyrba, Martin, et al.
Publicado: (2021)

Cholinergic white matter pathways along the Alzheimer's disease continuum
por: Nemy, Milan, et al.
Publicado: (2022)

Association between composite scores of domain-specific cognitive functions and regional patterns of atrophy and functional connectivity in the Alzheimer’s disease spectrum
por: Amaefule, Chimezie O., et al.
Publicado: (2020)

Amyloid pathology but not APOE ε4 status is permissive for tau-related hippocampal dysfunction
por: Düzel, Emrah, et al.
Publicado: (2022)

Long-term environmental enrichment is associated with better fornix microstructure in older adults
por: Klimecki, Olga M., et al.
Publicado: (2023)

Performance evaluation of automated white matter hyperintensity segmentation algorithms in a multicenter cohort on cognitive impairment and dementia
por: Gaubert, Malo, et al.
Publicado: (2023)

Prevalence of abnormal Alzheimer’s disease biomarkers in patients with subjective cognitive decline: cross-sectional comparison of three European memory clinic samples
por: Wolfsgruber, Steffen, et al.
Publicado: (2019)

Arterial hypertension and β-amyloid accumulation have spatially overlapping effects on posterior white matter hyperintensity volume: a cross-sectional study
por: Bernal, Jose, et al.
Publicado: (2023)

Higher CSF Tau Levels Are Related to Hippocampal Hyperactivity and Object Mnemonic Discrimination in Older Adults
por: Berron, David, et al.
Publicado: (2019)

Novelty-Related fMRI Responses of Precuneus and Medial Temporal Regions in Individuals at Risk for Alzheimer Disease
por: Billette, Ornella V., et al.
Publicado: (2022)

Musical Activity During Life Is Associated With Multi-Domain Cognitive and Brain Benefits in Older Adults
por: Böttcher, Adriana, et al.
Publicado: (2022)

A microRNA signature that correlates with cognition and is a target against cognitive decline
por: Islam, Md Rezaul, et al.
Publicado: (2021)

Locus coeruleus MRI contrast is reduced in Alzheimer's disease dementia and correlates with CSF Aβ levels
por: Betts, Matthew J., et al.
Publicado: (2019)

Midlife occupational cognitive requirements protect cognitive function in old age by increasing cognitive reserve
por: Kleineidam, Luca, et al.
Publicado: (2022)

Diagnosis and biomarkers of predementia in Alzheimer's disease
por: Forlenza, Orestes V, et al.
Publicado: (2010)

Dietary Fatty Acids and Predementia Syndromes
por: Solfrizzi, Vincenzo, et al.
Publicado: (2009)

Cerebral perfusion in the predementia stages of Alzheimer’s disease
por: Binnewijzend, Maja A. A., et al.
Publicado: (2015)

Bupropion for the Treatment of Apathy in Alzheimer Disease: A Randomized Clinical Trial
por: Maier, Franziska, et al.
Publicado: (2020)

Enrichment and Stratification for Predementia Alzheimer Disease Clinical Trials
por: Holland, Dominic, et al.
Publicado: (2012)

Automatic speech analysis for the assessment of patients with predementia and Alzheimer's disease
por: König, Alexandra, et al.
Publicado: (2015)

Apathy and the Risk of Predementia Syndromes in Community-Dwelling Older Adults
por: Ceïde, Mirnova E, et al.
Publicado: (2020)

Cerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline
por: Bos, Isabelle, et al.
Publicado: (2017)

Resource utilisation and costs in predementia and dementia: a systematic review protocol
por: Landeiro, Filipa, et al.
Publicado: (2018)

Whole-body modelling reveals microbiome and genomic interactions on reduced urine formate levels in Alzheimer’s disease
por: Martinelli, Filippo, et al.
Publicado: (2023)

Correction to: Cerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline
por: Bos, Isabelle, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_74ik5qiukkfmn5hrevr0svrvod